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Glutathione has been referred to as the mother of all antioxidants. Glutathione is a combination of three amino acids: cysteine, glutamic acid, and glucine

Phylum-level analysis (Figure S1D) revealed that the VPA-ASD group was dominated by Pseudomonadota (Proteobacteria), with elevated Deferribacterota and Campylobacterota, and severe depletion of Bacteroidota and Verrucomicrobiota

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A low SAM/SAH ratio may result from insufficient SAM, elevated SAH or both

The mechanism is not well established it may relate to individual sensitivity, dehydration coinciding with supplement use, or other unrelated factors