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Challenges and perspectives Biodistribution, pharmacokinetics, and safety The clinical translation of GLP-1R-targeted nanotherapeutics hinges on effectively addressing challenges related to biodistribution, pharmacokinetics, and safety

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Notice that two of these, gallstones and alcohol, have nothing to do with the GLP-1 mechanism, and the third, triglycerides, often improves on treatment

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doi:10.1097/gme.0b013e31824f606e

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