Phase II pathways attach glutathione, glucuronic acid, sulfate, glycine, taurine, acetyl groups or methyl groups
Venditti et al., 2013)
Rather than examining oxidative damage in isolation, the researchers tracked a comprehensive panel of readouts: tissue lipid peroxidation, tissue glutathione status, serum lipid profiles, hormonal markers (testosterone, T3, and T4), and trace mineral concentrations (copper and zinc) across multiple compartments
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The oxidative stress caused by a decrease in GSH levels can then impact microglia function and potentially lead to a more pro-inflammatory M1 phenotype that has reduced -amyloid clearance capabilities (Vilhardt et al., 2017)
Exploring these peptides has been an incredible journey for me, and I hope this deeper dive gives you a clearer picture of what Thylamin, Epitalon, and the others can offer in your anti-aging strategy