Martnez de Toda I, Gonzlez-Snchez M, Daz-Del Cerro E, Valera G, Carracedo J, Guerra-Prez N
Due to the high expression profile of GLP-1R in pancreatic -cells, GLP-1 analogs (such as exendin-4) have been modified by different methods (to prolong half-life, maintain receptor binding affinity and reduce renal drug accumulation) for theranostic purposes and serve as excellent templates for future cardiovascular drug development[178-184]
Anyone considering peptide research should work within their applicable regulations and seek qualified medical guidance
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