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Tirzepatide (sold as Mounjaro and Zepbound) uses a similar step-up approach, starting at 2.5mg and increasing to 15mg maximum

Retatrutide for the treatment of obesity, obstructive sleep apnoea and knee osteoarthritis: rationale and design of the TRIUMPH registrational clinical trials

And we do not know that retatrutide the molecule is dangerous, because in the relevant sense it almost certainly is not

Alternatives include other classes of diabetes medications, such as SGLT2 inhibitors and DPP-4 inhibitors, as well as lifestyle interventions like diet and exercise

They also offer compounded injectible GLP-1s like semaglutide, at a lower cost than the brand name medications

It's important to understand that stopping semaglutide does not cause immediate weight gain, but it removes a significant tool that was helping to maintain weight loss