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Q: What about the drugs effectiveness against other conditions

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The FAERS database is subject to reporting bias, lacks denominator data (total number of patients exposed), and cannot distinguish between coincidental associations and true drug-related effects

These conditions and causes include emphysema, asthma, allergic disorders, drug toxicity, metabolic disorders, cancer, chemotherapy and human immunodeficiency virus-acquired immune deficiency syndrome, among others

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FIDELIO-DKD demonstrated a significant reduction in kidney failure and CV outcomes (HR 0.82 for the primary kidney composite), complemented by FIGARO-DKD and consolidated in the FIDELITY pooled analysis, which showed a 23% reduction in major kidney outcomes and a consistent effect across CKD stages