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The meta-analysis of Heydarpour et al., which reviewed five high-quality trials involving 448 women with PCOS, showed that cinnamon supplementation decreased fasting blood sugar, fasting insulin, and HOMA-IR [200]

Another drug Tamoxifen, that was originally known for its ability to increase fertility, was repurposed for breast cancer therapy

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Hypoglycaemia: While the risk is lower than with insulin or sulfonylureas, caution is warranted in people with type 2 diabetes, particularly those on concomitant glucose-lowering agents

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