Initially developed in the 1960s as a mucolytic agent (Figure 1)
Continue onto the GLP-1 maintenance program with 1-2 injections per month
It is not recommended for those with seizure disorders or uncontrolled hypertension
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A 2023 pharmaceutical stability study demonstrated that tirzepatide kept at room temperature for 48 hours showed measurable loss of active compound, compromising clinical efficacy and treatment outcomes
Rhee CM, Ahmadi SF, Kovesdy CP, Kalantar-Zadeh K