The Effect of Antioxidant Supplementation in Patients with Tinnitus and Normal Hearing or Hearing Loss: A Randomized, Double-Blind, Placebo Controlled Trial
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L-ascorbic acid requires a low pH (typically below 3.5) to remain stable, and that acidic environment can disrupt the copper complex in GHK-Cu, potentially degrading both ingredients
J., Bucknall, R
Its copper-mediated influence on lysyl oxidase activity, an enzyme critical to collagen cross-linking, is one proposed mechanism underlying these observations