Regular follow-up visits should be individualized based on response, tolerance, and comorbidities
The STEP clinical trials the largest studies ever conducted on semaglutide, found that nausea typically resolves within the first two weeks, diarrhea clears within days, and even constipation, the most persistent GI side effect, averages around 47 days before it improves
N Engl J Med 2021;384:1113-1124
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