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This concern is more relevant for diabetic users than for those using tirzepatide primarily for weight management
While the IOM had based B12 needs on the amount required to correct hematological parameters for people with pernicious anemia, the EFSA had almost 20 more years of research to draw on, and concluded that the most suitable approach was basing needs on biomarkers (serum B12, holotranscobalamin, MMA, and homocysteine)
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are or were previously employees and stockholders of Amgen