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PubMed laboratory research record [PMID: 15663752] PubMed record related to this compound for laboratory literature review
[4] [5] It has been encountered as a designer drug mainly in racehorses, [6] but is also prohibited for use by athletes in competition by the World Anti-Doping Agency, and is classified as a prescription medicine in some jurisdictions such as Australia and New Zealand
Metformin activates the AMPK signaling pathway, which enhances mitochondrial function, limits mitochondrial ROS production, and promotes antioxidant defense through downstream stimulation of Nrf2-dependent cytoprotective genes
doi: 10.3390/JCM11247314 147 KandemirHBlblGAKirtiEGneySSanhalCYMendilcioluIIet al
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