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Proposed mechanisms for hepatocyte necrosis include extreme hypertrophy leading to reduced sinusoidal blood circulation, hypoxia, and necrosis (Slauson and Cooper 2001) and/or metabolic activation forming more toxic active metabolites (Farber 1980)

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Vitamin C supplements are pretty safe to take, even in high doses

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Can I skip the titration and start at a higher dose

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May be more bioavailable than supplemental glutathione itself

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The Phase 3 CagriSema program (REDEFINE 1, 2, REIMAGINE 2) capped cagrilintide at 2.4 mg per week

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Facilities should have emergency protocols and equipment available to handle potential complications

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