Downregulation of ASS1 caused by promoter methylation increases the susceptibility of tumor cells to PEGylated arginine deiminase (ADI-PEG20) (Table 1), a drug for arginine-deprivation treatment that has been used in clinical trials for a variety of tumors (Delage et al., 2012
Oxidative stress, marked by an imbalance between free radicals and antioxidants, is implicated in IBD pathogenesis
Kidney tissues exhibited histopathological changes including tubular cloudy swelling, hydropic degeneration, epithelial desquamation, tubular necrosis, interstitial congestion, hemorrhage, and intraluminal cast formation in more affected groups
She is also registered with the Nursing and Midwifery Council (NMC) and holds an Independent Nurse Prescribing (INP) qualification
It is considered one of the most advanced peptides in the field of anti-aging and cellular rejuvenation
In sensitive individuals, it may increase irritation or discomfort