Kaplan recommends increasing fluid intake to soften stools and promote easier bowel movements
Despite the successful trial, 10.6% of participants discontinued the 36mg and 12mg treatment due to adverse effects, compared to 4.6% in the placebo group
doi:10.1159/000115711
That's a reason to keep on top of your nutrition and strength-training while on these drugs, he writes, "especially for older people like me, who are [already] susceptible to muscle loss." There are people who should steer clear of GLP-1 drugs, Kessler notes, including those with a personal or familial history of certain thyroid and endocrine cancers, those with chronic kidney disease, pancreatitis, inflammatory bowel diseases, uncontrolled diarrhea or constipation or gastroparesis, or if you are pregnant
It is composed of three specific amino acids: cysteine, glutamate, and glycine
We begin with the scientific background tracing the incretin concept from early 20th-century experiments through the discovery of GLP-1 in the 1980s