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Key findings include: Upregulation of VEGFR2 expression and internalization in endothelial cells Activation of the VEGFR2-Akt-eNOS signaling cascade Enhanced endothelial cell proliferation and tube formation Improved collateral circulation in ischemic injury models The peptides pro-angiogenic effects appear particularly relevant in healing scenarios where blood supply restoration is critical for tissue recovery

What is your current level of comfort with prescribing GLP-1 injectable medication for the treatment of T2DM

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Neither agent individually holds MHRA marketing authorisation, and both remain in clinical development