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Therefore, we aimed to identify factors affecting PK variability of busulfan in pediatric allogeneic hematopoietic cell transplantation (HCT) recipients and investigate the effect of glutathione S-transferase (GST) activity on busulfan metabolism using a semi-mechanistic population PK model

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Long-term existence of SARS-CoV-2 in COVID-19 patients: host immunity, viral virulence, and transmissibility

In diabetic neuropathy, chronic hyperglycemia leads to peripheral nerve injury, altered nerve Fiber Na + , K + -ATPase activity, reduced nerve conduction velocity and the release of ROS which leads to the activation of NLRP3 inflammasome (Niulescu et al

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Results were presented as pictogram or nanogram of mediator released per milliliter of conditioned medium