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Against this backdrop, researchers explored GLP1 receptor agonistsa class of medicines widely used for diabetes and obesityfor potential neuroprotective and antiinflammatory effects in the brain
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36 ChatterjeeA.TaoH.ShibataY.MoritaM
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These hydroxylation reactions also require Fe 2+ as a cofactor, O 2 as a cosubstrate and ascorbic acid (vitamin C) as a reductase, which restore the activity of 2-OGDD enzymes (Fig
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