Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray: a double-blind placebo-controlled cross-over study
Chatterjee R, Davenport CA, Vickery EM, et al
Specifically, this meta-analysis combined the results of 19 clinical trials of vitamin E supplementation that mostly focused on secondary prevention and, as such, included subjects with pre-existing conditions, including heart disease, end-stage renal failure, and Alzheimer's disease
In fact, most people are able to get enough vitamin B12 through diet alone
But the effectiveness can vary based on individual skin biology, pigmentation levels, and overall health
If you are worried the shot will be painful you can rest assured that most clients find the discomfort negligible