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doi: 10.1016/j.molmet.2020.101102 23 AstrupACarraroRFinerNHarperAKunesovaMLeanMEJet al
93 Although berberine has been studied and shown to have a high level of safety in human clinical trials, concerns about its long-term use have been raised on the basis of preclinical studies that suggest long-term berberine use, especially at high doses, may impair cellular metabolism in specific types of cells
Cold temperature aids passive dissolution without damaging the peptide
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