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These mechanisms are described as research areas, not clinical outcomes
Despite best efforts with dosing and titration, some people cant tolerate GLP-1 medications
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Others have demonstrated that the positive outcomes of obesity surgery (i.e., changes in body weight and improved glucose homeostasis) are sustained in mice in the absence of GLP-1R or Y2-R, or both GLP-1R and Y2-R 66,67
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