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Markovic, J

LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: A phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial

Small number of research groups : A limited number of research groups have conducted most studies, which may affect the generalizability of the results

Clinical studies document sustained improvements over extended use

K-means clustering of amplicon sequence variant data confirmed that 5-Amino-1MQ treatment generated a distinct cecal microbiome profile from all other treatment groups including diet-switched vehicle controls indicating that NNMT inhibition produces microbiome changes that are separable from those produced by dietary composition alone

Bock-Marquette, I., Saxena, A., White, M