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10.1016/S0887-8994(02)00460-5 Shapiro YG, Gutman A: Muscle carnitine deficiency in patients using valproic acid
Prog Neurobiol (2004) 72:26393.10.1016/j.pneurobio.2004.03.003 60 BassoNPagliaNStellaI
Overall, clearance of MHD is split ~50/50 between hepatic and renal clearance
They also have an alkalinizing effect on the body meaning they make it less acidic which promotes muscle mass maintenance
Prompt disposal protects patients from severe health complications
Lancet 376 , 393394 (2010)
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