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Ann Rev Nutr 1986

While some users report positive outcomes, others have found the peptide to have little or no effect on their sleep, anxiety, or stress levels

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The semaglutide group showed a significantly improved Kansas City Cardiomyopathy Questionnaire clinical summary score and a longer 6-min walking distance from baseline (21.5 m and 1.2 m in the semaglutide and placebo groups, respectively, intergroup difference 20.3 m, 95% CI 8.632.1 m), compared with that in the placebo group despite the relatively short observation period of 52 weeks

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Statistical analysis was performed in GraphPad Prism 7 using one-way analysis of variance (ANOVA) for comparison followed by Dunnetts multiple comparison test where applicable