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In brief, chemical standard libraries of 149 metabolites in seven pooled libraries were prepared and serially diluted in high-performance liquid chromatography (HPLC)-grade water from in a dilution series from 5 mM to 1 M to generate external standard pools, which are used for calibration of isotopically labelled internal standards and to quantify concentrations of metabolites for which internal standards were not available
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Ako u vyplynulo z informci uvedench vyie, najvnejm dsledkom nedostatku pecializovanej aminokyseliny L-karnitnu je naruen energetick metabolizmus
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