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Modules correlated with the KO genotype were enriched for neuronal and synaptic genes involved in vesicle-mediated transport, neurotransmitter secretion, and GTPase activity, suggesting that RAMP deletion disrupts synaptic signaling networks critical for metabolic regulation [2]

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Flow cytometry revealed pronounced skewing of CD11b + BMDMs from M2 to M1, complete ablation of myeloid-derived suppressor cells (MDSCs) and expanded neutrophil/monocyte subsets (Fig

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