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Literature references: Pizzorno J

For subcutaneous human use in the research-compound context, practitioners typically report timelines similar to topical: noticeable changes from 4 weeks, more pronounced at 8 to 12 weeks

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The hair evidence is interesting, but earlier than the marketing suggests

Singh et al., 2022)

Both TIn and Alk-TIn strongly inhibited the activity of mTYR with IC 50 values of 51.1 nM and 92.6 nM, respectively, which were both much lower than the commercial TYR inhibitor kojic acid (34.1 M) (Supplementary Fig