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85 The resulting increase in membrane unsaturation markedly enhances cellular susceptibility to lipid peroxidation and ferroptotic injury, thereby lowering the threshold for propagation once oxidative signals are initiated

Nicotinamide Adenine Dinucleotide (NAD+) supports cellular energy, metabolism, and longevity

GSH Quantification Glutathione and GSSG were measured in lysates from cells in 6-well plates as previously described ( ROS Quantification by Spin-Trapping and EPR Spectroscopy Cells (5 10 6 /0.1 ml) were stimulated for 2 h with LPS, then incubated with 50 mM 5-tert-butoxycarbonyl-5-methyl-1-pyrroline-N-oxide (BMPO), synthetized as described previously ( Cell Viability Assay Cells were seeded in 96-well plates at 25,000/well in complete medium

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Consult a healthcare professional if severe side effects occur