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CL Answer Which supplements and lifestyle changes improve sleep, and which cause insomnia
However, their therapeutic effects extend beyond glycemic control, particularly in weight management and metabolic disorders
Some in vivo and several in vitro studies demonstrated an antioxidative effect of L-carnitine supplementation resulting in reduced intracellular ROS production or modulation of NADPH oxidase activity (50, 5456)
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They are not medicines or drugs, have not been evaluated or approved by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease
The trial in people with T2D included 281 participants (mean age 56 years, 56% women, mean BMI 35.0 kg/m 2 , mean HbA1c 8.3%) treated with lifestyle only and/or metformin, with similar intervention arms to the obesity trial, albeit retatrutide 0.5 mg rather than 1 mg, and dulaglutide 1.5 mg was an additional comparator [46]
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