semaglutide 2.4 mg obesity 50 of oral #semaglutide daily was associated with body weight reduction and improved cardiometabolic risk factors in East Asian adults with overweight or #obesity, with or without type 2 #diabetes. https://ja.ma/41sPiYj Two-year effects of semaglutide in

Bult, J.A

One of the surprising findings is that high blood sugar can ultimately decrease glucose availability in the brain

We believe that a better understanding of the reasons could help address the barriers to continued use of these medications. Their cross-sectional study examined electronic health record (EHR) data of 288 patients with overweight or obesity and without type 2 diabetes who initiated injectable semaglutide or tirzepatide and discontinued treatment within the first year, 145 of whom received semaglutide, and 143 tirzepatide

These drugs mimic a hormone made in the gut

A simple "two capsules per day" regimen appeals to people who don't want to mix powders or commit to complicated meal replacement programs

This is why oral doses are expressed in larger milligram numbers even though less of the drug reaches the bloodstream per dose