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A Randomized Crossover Intervention Study on the Effect a Standardized Mat Extract (Ilex paraguariensis A

Over the following weeks, patients often report smoother movement, improved tissue quality, and faster recovery from disc irritation, joint inflammation, or tendon strain

Its effects contribute to improved tissue adaptability and long-term structural integrity

While human data is more limited, case reports from 2025-2026 suggest similar benefits in clinical practice, with women reporting improved mobility and reduced pain during menstruation

Harada H, Nishiyama Y, Katoh A, Niiyama H, Iwaki A, Ohchi Y, et al

JAMA 330 , 20752083 (2023)