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GLP-1RA Therapy as a Chronic Flux Perturbation System-Level Energy Flux Reorganization Under Weight Loss Therapy Most weight-loss interventionsincluding exercise [49], calorie restriction [50], cold exposure [51], and selected antidiabetic agents [10, 52]ultimately increase reliance on FAO, which supplies acetyl-CoA to sustain tricarboxylic acid (TCA) cycle activity and electron transport chain (ETC)coupled adenosine triphosphate (ATP) production
doi: 10.1074/jbc.M303948200 315 ChowdhuryIHKoyanagiYSuzukiMKobayashiSYamaguchiKYamamotoN
Zhang Y, Yu S, Yeernuer D, Liu W, Xu Z, Feng W, et al
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Under oxidative stress, methionine can be converted into cystine through the sulfur transfer pathway, and then GSH can be synthesized to further exert its antioxidant effects 31
doi: 10.1519/JSC.0b013e3182a76790
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