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Nicotinamide N-methyltransferase (NNMT) is an enzyme that plays a crucial role in cellular metabolism and energy homeostasis
Vitamin B12 plays a vital role in converting food into energy that powers your body functions
Support brain function and mood
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
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