Despite reasonably successful progress in clinical trials of its most advanced oral candidate danuglipron, the company halted development in April, owing to a possible drug-induced liver injury in one participant of an earlier study
Additionally, the general reduction in oxidative stress protects chloroplasts from damage, preserving and potentially enhancing chlorophyll synthesis and stability
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The associated SNP, rs10305420, is a missense variant in the signal peptide of the GLP1R gene, changing the seventh amino acid from proline to leucine (p.Pro7Leu)
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