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Conclusions In conclusion, in children and adolescents with obesity, GLP-1 receptor agonists significantly reduced BMI z-score, waist circumference and body weight
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Semaglutide is an FDA-approved GLP-1 (glucagon-like peptide-1) receptor agonist that helps to control blood glucose levels and assists in long-term weight loss
MOTS-c activates AMPK pathways that enhance metabolic function
Protein synthesis in muscle tissue increases, providing an anabolic signal that counteracts the catabolic environment created by caloric deficit
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