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On GLP-1 medications, you're fighting three dehydration mechanisms simultaneously: Reduced thirst signaling (central appetite suppression affects thirst centers) Reduced fluid intake with meals (nausea makes drinking unpleasant) Ongoing fluid loss from glycogen metabolism during weight loss The result is chronic mild dehydration in a substantial portion of patients during titration
The common factor is that they dont follow FDA-approved dosing protocol
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Kirkegaard, and S
10.1007/s12035-012-8251-3 Mol
Chronically elevated fasting blood glucose levelsor recurrent, excessive spikes in glucose levels after mealscan lead to devastating long-term consequences such as heart disease, blindness, kidney failure, liver disease, and cancer
Open Pathology J 3:3842 Jomova K, Valko M (2011) Advances in metal-induced oxidative stress and human disease
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