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Thus, we systematically mapped brain activation induced by intraperitoneal (i.p.) administration of liraglutide with immunohistochemistry for c-Fos, an early marker of neuronal activity

Emerging GLP-1 Vision Side Effects : With the emerging evidence linking GLP-1 and vision loss, plaintiffs allege the manufacturers of these drugs new of the risk of severe GLP-1 vision problems failed to inform patients or doctors and therefore they made and uninformed decision and had they know of the risk, they would have chosen not to take drugs that cause GLP-1 eye problems and lead to permanent blindness

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The most cited single result is from Yun and colleagues in 2018, who showed that NLY01, a long-acting PEGylated GLP-1R agonist, blocked the microglia-driven conversion of resting astrocytes into the neurotoxic A1 phenotype in mouse models, a process implicated in neuronal death in both Parkinsons and Alzheimers disease [4]

Medication can play a role, but it is rarely the entire story