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2 DPP-4 inhibitors are one of the two incretin-based medication classes

The two compounds represent distinct mechanistic approaches to metabolic research and are not directly interchangeable in protocol design

GLP-1s, which often reduce muscle No diet or exercise changes required during the trial Stock jumped 116% CEO Paul Bolno: WVE-007 could become once- or twice-yearly monotherapy, add-on, or maintenance post-GLP-1 therapy. 2 Structure Therapeutics: Oral GLP-1 Challenger Steps Into Phase 3 120 mg aleniglipron achieved 11.3% placebo-adjusted weight loss at 36 weeks No plateau observed Discontinuation rate only 10.4% Shares surged 107% CEO Raymond Stevens: Data suggest potentially best-in-class among oral small-molecule GLP-1s