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The few studies that exist are very small, low-quality, or were only tested on animals and cellsnot humans
We understand that
Because of this, it is very important to understand if you are deficient and to replace your levels if you are
Methionine - Contraindications
Alcoholism impairs B12 status, so counsel on alcohol use
If low energy is the reason you are looking beyond GLP-1 medication, start by asking what is causing it: lower intake, dehydration, a possible nutrient gap, or the dose adjustment itself
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