Vitamin B12, Vitamin C, B-Complex, B-6, and more
Reported or proposed issue Stomach upset with oral capsules Evidence source Informal community reports Known or theoretical
Studies as early as 1998 validate the use of correct oral treatment as being equally effective as injections, with a conclusion that stated: In cobalamin deficiency, 2,000mcg of cyanocobalamin administered orally on a daily basis was as effective and may be superior for raising blood B12 levels as 1,000mcg administered intramuscularly on a monthly basis
B12 helps produce the amino acid tryptophan, which is a big part of what makes us fall asleep at night
None of these pharmacological actions directly involve vitamin B12 metabolism or supplementation
However, UCLA Health reports that the broader at-risk population those with suboptimal or marginally low levels may reach up to 20% of adults over 60 (2022)