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The distinction worth understanding is this: prescription GLP-1 medications directly activate GLP-1 receptors and carry FDA approval based on extensive clinical trials
Semaglutide medications such as Ozempic and Wegovy can help with weight management and blood sugar regulation, but a new study suggests they may also be effective for treating a common skin condition associated with obesity
The Phase 2 data is genuinely impressive 24% body weight reduction over 48 weeks, with a safety profile broadly consistent with approved GLP-1 therapies, is a meaningful advance over anything currently on the market
The appetite suppression may feel similar, but the metabolic activation and energy expenditure effects are unique to retatrutide
Some clinical trials have looked at how it works during these times, but the effect on the unborn baby is still not fully known
Katzenstein et al
