(IV) The metal nanomedicines show great potential for cancer therapy not only because of the capability of GSH exhaustion, but also for their wide range of other biological effects, such as interference with osmotic pressure, regulation of the immune system, and activation of biocatalysis (Hu et al., 2022)
With growth factor approaches: GHK-Cu stimulates bFGF and collagen and may work with platelet-rich plasma (PRP) or controlled growth factor delivery to improve tissue remodeling in the uterus or ovary
AMPK which is activated by starvation and metformin activates the catabolic pathway and inhibits the anabolic pathway (Zhang et al
While the results show great promise, significant challenges remain in reducing algorithmic bias across demographic groups, validating performance with diverse external datasets, prospective clinical evaluations, standardization of performance metrics, and clear regulatory pathways towards deployment (203, 204)
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The observed biological actions of GHK-Cu are extensive and highly relevant to skin health
