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Contraindications Tirzepatide should not be used by individuals with certain medical conditions due to potential health risks: People with a personal or family history of medullary thyroid carcinoma (MTC) should not use tirzepatide, because the medication may increase the risk of tumor growth in the thyroid gland

Importantly, recent reports showed that about 211% of patients with COVID-19 had underlying chronic liver disease (Jothimani et al., 2020) and that abnormal liver function is rather common in the course of the malady

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There is a need for more specific guidelines tailored to the unique characteristics of different Asian populations