Hypothyroidism, insulin resistance, obstructive sleep apnea, and medications such as corticosteroids can contribute to weight loss stabilization and persistent hyperglycemia
If you're resistant to GLP-1, you're not getting its appetite-suppressing effects, which makes you more likely to eat more junk food, which only adds to the blood sugar problems that are keeping you resistant to GLP-1 in the first place
High expression of NLRP3, GSDMD, caspase-1, IL-18, and IL-1 has been observed in ovarian tissues of POI animal models (Khallaf et al., 2023
However, despite their benefits, single GLP-1RAs have limitations
Overdose with semaglutide may be associated with gastrointestinal effects such as nausea, vomiting and diarrhoea, which could lead to dehydration
Dosing units for hCG do not apply to GHK-Cu