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In another randomised controlled trial, there was an increased incidence of cholelithiasis in patients receiving once daily liraglutide 3mg compared with placebo (0.45% vs 0%) during the 12 months (2)
Keep Meals Smaller For reflux, fullness, or GLP-1 symptoms, smaller meals may be more helpful than removing every sulfur-containing food
(Source: Truveta, May 2026) Important limitation from the researchers themselves: This analysis covered only semaglutide and tirzepatide, and did not account for other common PCOS treatments such as metformin, combined oral contraceptives, or anti-androgen therapies
If you have a history of disordered eating, discuss an appropriate monitoring plan with your healthcare provider to ensure tracking doesn't trigger unhealthy behaviours
Decreases in multiple fatty acid metabolites were observed at 24 weeks, linked with obesity
Nausea can also change the experience
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