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The damage can range from a non-detectable injury over limited traumatic annular tears or nucleus pulposus prolapse to a complete destruction of the disc organ such as in fracture dislocations

Value per milligram: The sticker price does not exactly reflect the vials value

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Cell and Tissue Research , 377 (2), 153159

Routes reported in the literature include intravenous, subcutaneous, and intraperitoneal administration in animal models, with intravenous infusion common in the early human studies