Continuous exposure to any signaling molecule can lead to receptor downregulation, meaning the body responds less strongly over time
Some weight regain can still occur, even when a person follows consistent nutrition and activity habits
Atindra Bhatnagar Address House No.33, Rivera Town, Mata Mandir, Bhopal, Madhya Pradesh, 462003, India Report incorrect details
10.1016/j.ijmm.2012.07.008 68 Flores-VillegasA
Notably, the same meta-analysis highlighted that liraglutide, particularly when compared to higher doses of semaglutide or tirzepatide, promoted weight loss without a clinically meaningful reduction in lean mass [77]
Heliyon 10 (23), e40674