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These individuals may experience various complications, such as cardiovascular disease (including type 2 diabetes, hypertension, and hyperlipidemia), metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic syndrome (MS), and endometrial cancer (EC) ( 3.4.1 Protective effects of metformin on cardiovascular disease risk in patients with polycystic ovary syndrome Epidemiological research suggests that individuals with PCOS exhibit a greater prevalence of hypertension compared to those without PCOS, particularly among females of reproductive age, and their cardiovascular risk is notably elevated irrespective of their BMI

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