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Aardvark Therapeutics Sector: Oral gut-restricted bitter taste receptor agonists for hunger suppression HQ: San Diego, CA Year Founded: 2017 Origin Story: Aardvark Therapeutics was founded around a mechanistically distinct hypothesis: rather than suppressing appetite like GLP-1 drugs, the companys lead compound activates bitter taste receptors (TAS2Rs) confined to the gastrointestinal tract to trigger local release of satiety hormones, targeting hunger itself without systemic drug exposure

Unlike many toxins that are blocked by the blood-brain barrier, certain mycotoxins can penetrate this protective shield, directly accessing our neural tissue

The research team then calculated the wet/dry ratio of each specimen in order to compare them to the values of the control groups

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