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Lipohypertrophy is the accumulation of fat tissue into a rubbery lump, caused by repeated insulin or peptide injections in the same location over weeks to months
This mechanism contributes to significant weight loss, which has been demonstrated in clinical trials
It is often found in a combination formulation with other skin lightening agents such as topical retinoids (to increase efficiency) and low potency topical steroids (to reduce irritancy)
In addition, IGF-1 receptor sensitivity and activation of the post receptor pathway were not evaluated in the majority of the study enrolling long-lived subjects
Injection-Site Reactions: Redness, itching, or pain at the injection site may occur
Jeff Brown insisted that she was given thyroid medication, despite not needing it
